Small challenges can activate cells’ protective systems. Scientists are exploring whether food compounds and medicines can make use of this effect.
Articles on Cell biology
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The goal of creating synthetic cells is not to replace nature, but to learn more deeply about biology and reengineer it to help society.
Studying why heart cells are less likely to become cancerous can provide clues to improving heart regeneration and treatments for heart disease.
Not only do mitochondria serve as the engine of the cell – they also act as watchtowers for the immune system.
Researchers discovered a previously unknown function of RNA, potentially opening the door to new ways to treat cancer and neurodegenerative diseases.
Membraneless organelles, also called biomolecular condensates, are changing how scientists think about protein chemistry, various diseases and even the origin of life.
Given the right conditions, certain types of cells are able to self-assemble into new lifeforms after the organism they were once part of has died.
As the powerhouse of the cell, mitochondria lie at the intersection of many essential biochemical pathways. When they go awry, neurodegenerative diseases can result.
Researchers can create ‘single-cell radios’ using bacterial proteins to transmit the invisible activities within cells.
Asthma attacks can result from immune cells overreacting to a harmless allergen. Tamping down iron levels in certain immune cells can help control their activity.
Sugar molecules called glycans cover the surface of all cells, acting as ID cards that broadcast what they are to the rest of the body.
Your cells die to keep you alive. Cell death does everything from fighting cancer cells and pathogens to forming your fingers and toes.
Superresolution microscopy allowed researchers to view cells at the molecular level. Improvements on the technique can help study the building blocks of complex cell processes over time.
Cell cultures are common tools in biology and drug development. Bringing them up to scale to meet the meat needs of societies will require further development.
Making sure RNA molecules are in the right place at the right time in a cell is critical to development and normal function. Researchers are figuring out exactly how they get to where they need to go.
Cells degrade and recycle damaged parts of themselves through a process called autophagy. When this “self-devouring” goes awry, it may promote cancer and neurodegenerative disease.
Many tumors have cancer stem cells that help them grow and evade treatments. Differentiation therapy forces these cells to mature, stopping growth with less toxicity than traditional treatments.
Many microscopy techniques have won Nobel Prizes over the years. Advancements like cryo-ET that allow scientists to see the individual atoms of cells can reveal their biological functions.
Preclinical studies are an important part of biomedical research, often guiding future trials in humans. Failure to replicate research results suggests a need to increase the quality of studies.
As people age, the chemical signaling pathways in muscles become less potent, and it gets harder to build muscle and maintain strength. But the health benefits of strength training only increase with age.
Top contributors
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Postdoctoral Research Fellow, Diamantina Institute, The University of Queensland
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Chair, The Conversation Media Group
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Professor of Mathematical and Evolutionary Computer Science, University of Hertfordshire
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Provost & Vice-President Academic, Laurentian University
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Professor of Mathematics, Heriot-Watt University
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Senior Faculty Member at the Garvan Institute, Conjoint Professor at UNSW, and Senior Principal Research Scientist, CSIRO
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Associate Professor of Biomedical Engineering, Georgia Institute of Technology
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Associate Professor, University of Warwick
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Cellular Agriculture PhD Candidate, Tufts University
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Assistant Professor, Neurodegenerative disorders, McGill University
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Professor of Pharmacy and Pharmaceutical Sciences, University of California, San Diego
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Postdoctoral Scholar of Pharmacy and Pharmaceutical Science, University of California, San Diego
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Postdoctoral researcher, Lysosomal Health in Ageing research group, South Australian Health & Medical Research Institute
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Postdoctoral fellow, Tufts University
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Jalview Coordinator, Bioinformatician and Open Source Software Developer, University of Dundee