Articles on Naloxone

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Critics of needle exchange programs often express concerns about syringe litter. Spencer Platt/Getty Images

Syringe litter did not increase after a needle exchange ban was overturned in Pueblo, Colorado, but health services suffered

Evidence suggests that people who receive syringes from a needle exchange are less likely to dispose of them improperly.
Administer naloxone right away if you suspect your dog is experiencing an opioid overdose. (Unsplash/Luke Macgillivray)

Dogs can overdose too: Naloxone training can save pets’ lives as well as humans

Naloxone is a safe and effective medication used to reverse the effects of an opioid overdose. It can be administered to dogs in either the nasal spray or injection formulations.
In March 2023, the U.S. Food and Drug Administration approved naloxone as a nonprescription nasal spray to reverse the effects of an opioid overdose. Michael Siluk/UCG/Universal Images Group via Getty Images

Animal tranquilizers found in illegal opioids may suppress the lifesaving medication naloxone − and cause more overdose deaths

Increasingly, these types of tranquilizers are turning up in fentanyl, oxycodone and other illegal opioids.
The use of naloxone administered by nasal spray can be a lifesaving drug with minimal side effects. TG23/iStock via Getty Images Plus

FDA approval of over‑the‑counter Narcan is an important step in the effort to combat the US opioid crisis

The Food and Drug Administration’s approval of Narcan will make the lifesaving drug more widely available, especially to those who might be likely to witness or respond to opioid overdoses.
Although xylazine is not an opioid, naloxone can reverse the effects of the fentanyl and heroin it is often mixed with. AP Photo/Jae C. Hong

What is xylazine? A medical toxicologist explains how it increases overdose risk, and why Narcan can still save a life

Xylazine, or tranq, is increasingly being mixed with drugs like fentanyl or heroin and can be difficult to detect. Most people who use drugs are unable to tell if they have been exposed to it.
Naloxone can prevent deaths from opioid overdose, but there is no way to reverse the effects of benzodiazepine overdose without risk. (THE CANADIAN PRESS/Jonathan Hayward)

‘Benzo‑dope’ may be replacing fentanyl: Dangerous substance turning up in unregulated opioids

Fentanyl adulteration led to the replacement of heroin in the unregulated drug supply of British Columbia. Now that benzodiazepines are present in many opioids, are we headed towards a ‘new normal?’
Annie Storey holds a cross with a photo of her late son Alex Storey, before a march to mark the five-year anniversary of British Columbia declaring a public health emergency in the overdose crisis, in Vancouver, on April 14, 2021. CANADIAN PRESS/Darryl Dyck

Overdose crisis: The COVID‑19 pandemic has laid bare decades of drug policy failures

Across the country, overdose deaths have spiked during the COVID-19 pandemic.

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