Daniel Kelly

17

Articles

6

Comments

Daniel Kelly is a senior lecturer in Biochemistry at Sheffield Hallam University with research interests in cardiovascular disease, type 2 diabetes, obesity and the role of testosterone in these diseases. Following his PhD studying the anti-inflammatory effects of testosterone on atherosclerosis, Daniel undertook a postdoc at the University of Sheffield to work with Professor Hugh Jones to investigate the tissue-specific actions of testosterone related to the pathogenesis of type 2 diabetes and cardiovascular disease. This research continues at Sheffield Hallam University and extends through on-going collaborations with partners at the University of Sheffield, University of Chile, Barnsley NHS foundation trust and Bayer Healthcare where he is currently using cell culture systems, pre-clinical models and medical trials of replacement therapy to uncover the underlying mechanisms of testosterone action. He has published in several high-impact journals in the field of endocrinology and acts as a reviewer for many of these journals. He is associate editor for the journal Androgens:Clinical research and Therapeutics.

Daniel has an honorary lectureship position at the University of Sheffield allowing close collaboration across the Sheffield Universities. He is the deputy course leader for the undergraduate Biomedical Science degree at Sheffield Hallam University where he uses his current and prior research to inform his teaching in areas related to metabolism, endocrinology, cell biology, and biological basis of disease.

Experience

  • 2018–present
    Senior lecturer, Sheffield Hallam University
  • 2016–2018
    Lecturer, Sheffield Hallam University
  • 2011–2016
    Postdoctoral research associate, Univesity of Sheffield

Education

  • 2010 
    Sheffield Hallam University, PhD
  • 2003 
    Aston University, Birmingham, BSc (hons) Human Biology and Psychology

Publications

  • 2023
    Testosterone treatment and change of categories of the International prostate symptom score (IPSS) in hypogonadal patients: 12 years prospective controlled registry study, Aging Male
  • 2023
    Testosterone and Covid-19: An update, Reviews in Medical Virology
  • 2023
    Voiding function improves under long-term testosterone treatment (TTh) in hypogonadal men, independent of prostate size, International Journal of Nephrology
  • 2022
    COVID-19 Crisis Timeline: The Warning and the Surge, Health Crisis Management in Acute Care Hospitals
  • 2022
    The effects of long-term testosterone treatment on endocrine parameters in hypogonadal men: 12-year data from a prospective controlled registry study, Aging Male
  • 2021
    Testosterone stimulates cholesterol clearance from human macrophages by activating LXRalpha, Life Sciences
  • 2021
    Sex-based differences in severity and mortality in COVID-19, Reviews in Medical Virology
  • 2020
    Long-term testosterone therapy improves liver parameters and steatosis in hypogonadal men: a prospective controlled registry study, Aging Male
  • 2018
    Randomized controlled trials - mechanistic studies of testosterone and the cardiovascular system., Asian Journal Andrology
  • 2016
    Testosterone differentially regulates targets of lipid and glucose metabolism in liver, muscle and adipose tissue of the testicular feminised mouse., Endocrine
  • 2015
    Testosterone and Obesity., Obesity Reviews
  • 2014
    Testosterone suppresses regulatory enzymes of fatty acid synthesis and protects against hepatic steatosis in cholesterol-fed androgen deficient mice. , Life Sciences
  • 2014
    Testosterone and cardiovascular risk in men., Vol. 43 Frontiers of Hormone Research
  • 2013
    Testosterone and insulin resistance in the metabolic syndrome and T2DM in men. , Nature Reviews Endocrinology
  • 2013
    Testosterone: A Metabolic Hormone in Health and Disease., Journal of Endocrinology
  • 2013
    Testosterone: A Vascular Hormone in Health and Disease., Journal of Endocrinology
  • 2012
    Effect of Testosterone on Inflammatory Markers in the Development of Early Atherogenesis in the Testicular-Feminized Mouse Model., Endocrine Research

Grants and Contracts

  • 2018
    Summer studentship
    Role:
    PI
    Funding Source:
    Society for Endocrinology
  • 2016
    Early Career Grant
    Role:
    PI
    Funding Source:
    Society for Endocrinology

Professional Memberships

  • Society for Endocrinology
  • The Endocrine Society
  • The Androgen Society

Contact Daniel for

  • General
  • Media request
  • Speaking request
  • Consulting / Advising
  • Research collaboration
  • Research supervision