Articles on Xylazine

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Patients who received 17 to 24 milligrams per day of buprenorphine stayed in treatment significantly longer than those who received 16 milligrams or less, researchers found. AP Photo/Julio Cortez

Higher buprenorphine doses help patients stay in opioid use disorder treatment, new study finds

Black patients were less likely to receive higher doses. This may reflect inequities in health care or misconceptions among patients that higher doses are unsafe.
In March 2023, the U.S. Food and Drug Administration approved naloxone as a nonprescription nasal spray to reverse the effects of an opioid overdose. Michael Siluk/UCG/Universal Images Group via Getty Images

Animal tranquilizers found in illegal opioids may suppress the lifesaving medication naloxone − and cause more overdose deaths

Increasingly, these types of tranquilizers are turning up in fentanyl, oxycodone and other illegal opioids.
Patients suffering withdrawal from fentanyl and xylazine can require intensive care. SDI Productions/E+ Collection via Getty Images

Philly hospitals test new strategy for ‘tranq dope’ withdrawal – and it keeps patients from walking out before their treatment is done

The combination of fentanyl and xylazine that dominates Philadelphia’s illegal dope supply creates agonizing withdrawal symptoms. This presents new challenges for doctors and nurses.
Although xylazine is not an opioid, naloxone can reverse the effects of the fentanyl and heroin it is often mixed with. AP Photo/Jae C. Hong

What is xylazine? A medical toxicologist explains how it increases overdose risk, and why Narcan can still save a life

Xylazine, or tranq, is increasingly being mixed with drugs like fentanyl or heroin and can be difficult to detect. Most people who use drugs are unable to tell if they have been exposed to it.

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