Articles on Human genome

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There is still a great deal unknown about RNA and its modifications. Christoph Burgstedt/Science Photo Library via Getty Images

RNA is key to the dark matter of the genome − scientists are sequencing it to illuminate human health and disease

Researchers are embarking on the RNA equivalent of the Human Genome Project, including sequencing all the chemical modifications that make cells unique.
New genome editing technologies mean that the genetic modification of embryos is a scientific possibility, and laws governing its practice require extensive public consultation. (Shutterstock)

South Africa amended its research guidelines to allow for heritable human genome editing

A recent change to South Africa’s national health research guidelines contains newly added language that appears to permit the use of genome editing to create genetically modified children.
The collective tomb at Bréviandes les Pointes, near Troyes, where all the skeletons have had their genomes sequenced. INRAP

A 4,500‑year‑old collective tomb in France reveals its secret – the final stage in the formation of a ‘European genome’

A new study reveals the final stage in the formation of the European genome, which is still present in many people today.
DNA editing has the capacity to treat many diseases, but how to do this safely and equitably remains unclear. KTSDESIGN/Science Photo Library via Getty Images

Human genome editing offers tantalizing possibilities – but without clear guidelines, many ethical questions still remain

Following the controversial births of the first gene-edited babies, a major focus of the Third International Summit on Human Genome Editing was responsible use of CRISPR.
Statistical pitfalls in GWAS can result in misleading conclusions about whether some traits (like long horns or spotted skin, in the case of dinosaurs) are genetically linked. @meanymoo

People don’t mate randomly – but the flawed assumption that they do is an essential part of many studies linking genes to diseases and traits

People don’t randomly select who they have children with. And that means an underlying assumption in research that tries to link particular genes to certain diseases or traits is wrong.

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